Simultaneous use of
these two drug classes can lower blood pressure considerably causing symptomatic
hypotension (e.g., fainting) in some patients. Concomitant treatment should be
initiated only if the patient is stable on his alpha blocker therapy. In those
patients who are stable on alpha-blocker therapy, levitra should be initiated
at a dose of 5 mg.
If you have mild
hepatic impairment (Child-Pugh A), and you want to take levitra, you can take
it without any adjustment in the dose. But patients who have moderate hepatic
impairment (Child-Pugh B) eliminate vardenafil in decreased amount. If you have
this condition you need a starting dose of 5 mg of this drug. You should not
take more than 10 mg at any cost. The consequence of taking this pill has not
been assessed in patients with severe hepatic impairment (Child-Pugh C).
If you have mild (CLcr = 50-80
ml/min), moderate (CLcr = 30-50 ml/min), or severe (CLcr<30 ml/min) renal problem, you need no dose adjustment. This
medication has not been studied in patients who require renal dialysis.